Balding men and women may fine an answer soon to grow more hair and replenish their follicular deficiencies. New experiment with humans and mice cells has succeeded to generate hair follicles the growth of the follicles.
Researchers have come up with a method to convert adult cells into epithelial stem cells, the first time anyone has achieved this in either humans or mice. When they mixed the epithelial stem cells with mouse follicular inductive dermal cells and implanted into immunocompromised mice, it regenerated the different cell types of human skin and hair follicles, and even produced structurally recognizable hair shaft, raising the possibility that they may eventually enable hair regeneration in people.
The new experiment shows regenerating mice cells to different cell types of human skin and hair follicles, and structurally recognizable hair shaft.
Xiaowei "George" Xu, MD, PhD, associate professor of Pathology and Laboratory Medicine and Dermatology at the Perelman School of Medicine, University of Pennsylvania, and colleagues published in Nature Communications a method for converting adult cells into epithelial stem cells. He is raising the possibility that they may eventually enable hair regeneration in people.
“When a person loses hair, they lose both types of cells.” Xu explains. “We have solved one major problem, the epithelial component of the hair follicle. We need to figure out a way to also make new dermal papillae cells, and no one has figured that part out yet.”